Portrait of Prof. Chris de Zeeuw, Scientific Coordinator of the BrainFrame research project

Prof. Chris de Zeeuw

Scientific Coordinator of BrainFrame, based at Erasmus University Medical Centre in Rotterdam, the Netherlands

Research field

Neuroscience, Brain Simulation

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“Why did I become hooked on brain research? I would say: why not? The human brain is the most beautiful organ that evolution produced”, states Professor of Neuroscience Chris de Zeeuw. His passion for brain science started in medical school, when he had a part-time job at the Department of Neurophysiology.


Simulating neural networks with a computer helps us better understand how the brain works. An important application of this research is brain rescue. If brain function can be simulated accurately, we may be able to develop brain prosthetics and implants. These could recover brain functionality lost due to disease or accidents.


“We aim to develop a rapid brain-simulation machine. This will allow neuroscientists to simulate neural networks of extremely large sizes (>1 million neurons) in high detail. The platform will be energy-efficient, affordable and intuitive to use for a wide range of researchers”, says BrainFrame lead scientist Christos Strydis.


Dr Strydis: "We are developing the BrainFrame concept to accelerate our own research. The European Commission has now awarded us a proof-of-concept grant to explore the commercialization of the platform. We will ensure its technical validity by testing for correctness, accuracy, simulation speeds and ease of programming use.”

Towards easy and affordable brain simulation

In the Picture
In the Picture
Image credits

Background image: 3D reconstruction of neurons from ZEISS Atlas dataset, mouse brain, ultrathin sections on wafer, ATUM preparation, image width 50 * 50 μm, ZEISS FE-SEM. Courtesy of Daniel Berger, Group of S. Seung, Dep. Brain and Cognitive Sciences, MIT. G. J. Lichtman, Molecular and Cellular Biology, Harvard, USA

Portrait of the project coordinator: BrainFrame

Timeline (in chronological order): 1890: Santiago Ramón y Cajal, 1943: Dr Jonathan Clarke / Wellcome Images, 1969: Benedict Campbell, Wellcome Images, late 2000s and 2015: BrainFrame